Common orthopedic procedures, such as hip and pelvic fracture surgery as well as spinal fusion, require the accurate positioning of a thin metallic wire to guide the positioning of a fixating screw. However, the surgical procedure is often hampered by deflection, bending, and even breakage of the guide-wire, which then requires repair while complicating and prolonging the recovery of patients. Researchers at the Hebrew University's BioDesign program developed BendGuide, an opto-electronic drilling system that monitors and detects minute changes in guide-wire trajectory during surgery. It allows surgeons to correct drilling trajectories during the procedure itself. The system eliminates guide-wire bending or breakage and significantly reduces operation time while increasing safety. BendGuide uses a fiber bundle with a reflecting laser beam that enables detection of small deflections in wire trajectory. At a fully-aligned state, the beam power hits the center of the detector array. When deflected, mirror misalignment causes the power to spread differentially across the fiber bundle.