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Looking Inside Blood Clots with ‘Optical Clearing Technique’
Although blood clots stop bleeding after injury, clots that block blood flow can cause strokes and heart attacks. A new technique that makes blood clots optically clear is allowing researchers from the University of Notre Dame and the University of California, Riverside to use powerful optical microscopy techniques to study the 3D structure of dangerous clots for the first time. The new approach could make it possible to use advanced light microscopy techniques such as confocal microscopy to correlate clinical symptoms with the 3D structure of clots from patients. It is common for cardiologists to remove blood clots blocking the arteries of people who have experienced heart attacks or strokes.
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